کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6483266 1 2016 32 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
NF-κB decoy oligodeoxynucleotide mitigates wear particle-associated bone loss in the murine continuous infusion model
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
NF-κB decoy oligodeoxynucleotide mitigates wear particle-associated bone loss in the murine continuous infusion model
چکیده انگلیسی
Upper panel, illustration of the murine model with continuous femoral infusion. Mouse distal femurs were exposed to ultra-high molecular weight polyethylene (UHMWPE) particles together with NF-κB decoy oligodeoxynucleotide (ODN) and appropriate controls. Lower panel, trabecular bone structure (blue square) in the distal femur was reconstructed into a 3D image. Yellow lines indicate the major bone loss area induced by UHMWPE particles. Green dotted circle indicated the inserted titanium rod channel from intercondylar region at distal femur. The number of infiltrated macrophages (Mac) and osteoclasts (OC) were determined by immunohistochemistry. UNT: Untreated control.112
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Acta Biomaterialia - Volume 41, 1 September 2016, Pages 273-281
نویسندگان
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