کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6486630 1416257 2018 32 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Characteristics and application of S1-P1 nucleases in biotechnology and medicine
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
Characteristics and application of S1-P1 nucleases in biotechnology and medicine
چکیده انگلیسی
3′-nucleases/nucleotidases of the S1-P1 family (EC 3.1.30.1) are single-strand-specific or non-specific zinc-dependent phosphoesterases present in plants, fungi, protozoan parasites, and in some bacteria. They participate in a wide variety of biological processes and their current biotechnological applications rely on their single-strand preference, nucleotide non-specificity, a broad range of catalytic conditions and high stability. We summarize the present and potential utilization of these enzymes in biotechnology and medicine in the context of their biochemical and structure-function properties. Explanation of unanswered questions for bacterial and trypanosomatid representatives could facilitate development of emerging applications in medicine.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biotechnology Advances - Volume 36, Issue 3, May–June 2018, Pages 603-612
نویسندگان
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