Green synthesis of water-dispersable palladium nanoparticles and their catalytic application in the ligand- and copper-free Sonogashira coupling reaction under aerobic conditions

• Green synthesis of Pd nanoparticles.
• Sonogashira coupling reactions of different aryl iodides using Pd nanoparticles in water.
• Catalyst was characterized using the powder XRD, TEM and UV–vis.
• Catalyst can be easily recovered and reused.

Pd nanoparticles were prepared from PdCl2 by green method and were characterized with UV–vis, XRD and TEM methods. Catalytic studies indicated that Pd nanoparticles exhibited high activity for ligand-, amine- and copper-free Sonogashira coupling between aryl iodides and terminal alkynes under mild and aerobic conditions. This method has the advantages of high yields, simple methodology and easy work up. More importantly, the catalyst exhibits high catalytic activity, superior cycling stability and excellent substrate applicability.

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