کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
65163 | 48384 | 2014 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Activation of sp3 and sp2 CH bonds of oxygen containing heterocyclic molecules for alkylation and arylation reactions catalyzed by an iron complex Activation of sp3 and sp2 CH bonds of oxygen containing heterocyclic molecules for alkylation and arylation reactions catalyzed by an iron complex](/preview/png/65163.png)
• An efficient iron(III) complex of a bis(amido)pyridine ligand for activation of sp3 and sp2 CH bonds.
• CC coupling of oxygen containing heterocyclics with various alkyl, allyl and aryl Grignard reagents.
• Activation of selective α CH bond at room temperature and within a short period of time.
• Low catalyst loading (0.02–0.2 mol%) and high turnover frequency (>1700 h−1).
Activation of both sp3 and sp2 CH bonds is reported using an efficient iron(III) complex (1) of a ligand (N2,N6-bis(2,6-diisopropylphenyl)pyridine-2,6-dicarboxamide: L). The iron(III) complex showed catalytic activity of CC coupling reaction of oxygen containing heterocycles, e.g. tetrahydrofuran (THF), with various alkyl, allyl and aryl Grignard reagents under ambient reaction conditions. Complex 1 demonstrated excellent activity and reactions were completed within 30 min to 1 h. A high turnover frequency (TOF) of 1700 h−1 using a low catalyst loading of 0.02 mol% was obtained for the reaction. Interestingly, the catalyst was selective in activation of the CH bond adjacent to the oxygen in various oxygen containing heterocyclic molecules to yield 2-substitituted products.
Figure optionsDownload high-quality image (98 K)Download as PowerPoint slide
Journal: Journal of Molecular Catalysis A: Chemical - Volume 392, October 2014, Pages 253–259