Chiral oxo-vanadium (+)-pseudoephedrine complex immobilized on magnetic nanoparticles: A highly efficient and recyclable novel nanocatalyst for the chemoselective oxidation of sulfides to sulfoxides using H2O2

• The first chiral VO(pseudoephedrine)@MNPs was easily synthesized and characterized.
• It catalyzed highly efficient chemoselective oxidation of sulfides.
• The catalyst allows for greener method while keeping high yields and low times.
• The catalyst was easily reused up to 20 runs without significant loss of activity.

The first chiral oxo-vanadium (+)-pseudoephedrine complex supported on magnetic nanoparticles Fe3O4 [VO(pseudoephedrine)@MNPs] as novel magnetically interphase nanocatalyst was designed and characterized using the most common techniques. VO(pseudoephedrine)@MNPs catalyzed the chemoselective oxidation of sulfides to sulfoxides using hydrogen peroxide as a green oxidant in high yields with 20–27% enantiomeric excesses under solvent-free conditions at room temperature. The catalyst was recycled up to 20 times with little loss of activity and enantioselectivity.

Chiral oxo-vanadium (+)-pseudoephedrine complex immobilized on magnetic nanoparticles Fe3O4: a highly efficient and recyclable novel nanocatalyst for the chemoselective oxidation of sulfides to sulfoxides using H2O2.Figure optionsDownload high-quality image (144 K)Download as PowerPoint slide