Synthesis of copper (II)-supported magnetic nanoparticle and study of its catalytic activity for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones

• CuCl2/Fe3O4-TEDETA was synthesized.
• CuCl2/Fe3O4-TEDETA was characterized by, FT-IR, XRD, TGA, TEM and SEM techniques.
• CuCl2/Fe3O4-TEDETA was employed for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones.
• Catalyst could be easily recovered using a magnet and recycled.

A magnetic nanoparticle supported efficiently catalyzes for condensation 2-aminobenzamide with aldehydes to afford the corresponding 2,3-dihydroquinazolin-4(1H)-one derivatives successfully in high yield. The reactions were carried out in ethanol under reflux conditions. The protocol proves to be efficient and versatile benign in terms of very easy work-up and reused seven times without significant loss of catalytic activity. The heterogeneous catalyst was characterized by FT-IR spectroscopy, thermogravimetric (TGA) analysis, powder X-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscope (TEM).

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