کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
657717 1458064 2014 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effects of short-pulsed laser radiation on transient heating of superficial human tissues
ترجمه فارسی عنوان
اثرات تابش لیزر کوتاه مدت بر روی حرارت گذرا از بافت های سطحی انسان
کلمات کلیدی
انتقال شعاعی، انتقال حرارت گذرا، برنامه های پزشکی بیولوژیک، هیپرترمی، روشهای محاسباتی، لیزر امپدانس اثرات ناخوشایند
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی جریان سیال و فرایندهای انتقال
چکیده انگلیسی

Transient radiative transfer effects are pertinent to thermal treatment of superficial cancer via short-pulsed laser irradiation. Importance of the transient effects arise from relatively strong scattering and long attenuation path of radiation in human tissues in the therapeutic window until the complete absorption. Our analysis is based on transport approximation for scattering phase function and the Monte Carlo method for solving the three-dimensional radiative transfer problem. Monte Carlo simulations are used to study applicability of the quasi-steady radiative transfer approach, and demonstrate that in the biomedical problem under consideration, the quasi-steady solution for absorbed radiation power is sufficiently accurate for laser pulse duration longer than 10 ps. The simulations for superficial tissues with embedded gold nanoshells, used to increase the local volumetric absorption, show that overheating of the nanoshells with respect to the ambient biological tissue is strongly dependent on the laser pulse duration. This effect becomes considerable for laser pulse duration shorter than 1–2 ns. The quasi-steady approach for radiative transfer results in significantly underestimated temperatures of human tissues for short laser radiation pulses. The latter is explained by a relatively strong reflection of the short pulsed radiation by highly scattering human tissues.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Heat and Mass Transfer - Volume 78, November 2014, Pages 488–497
نویسندگان
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