کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
659051 | 1458093 | 2012 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Numerical simulation on oxygen transfer in a porous scaffold for animal cell culture
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
جریان سیال و فرایندهای انتقال
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Detailed numerical simulations are performed for oxygen transfer around and within a circular scaffold for animal cell culture. The oxygen concentration distribution, minimum oxygen concentration within the scaffold and its corresponding location, as well as the Sherwood number are presented at different Darcy numbers, Reynolds numbers and Damkohler numbers. It is found that if the Reynolds number is increased from 1 to 30, the Sherwood number increases 1 time for a Darcy number of 5Â ÃÂ 10â6 while 34 times for a Darcy number of 5Â ÃÂ 10â4. The location of the minimum oxygen concentration is close to the centre of the scaffold when the Darcy number is smaller than about 5Â ÃÂ 10â5 or the Reynolds number is smaller than about 1, especially for the Damkohler number larger than O(10). The present study may provide useful guidance on design of the bioreactor with scaffold as well as choosing optimal operating parameters.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Heat and Mass Transfer - Volume 55, Issues 15â16, July 2012, Pages 4043-4052
Journal: International Journal of Heat and Mass Transfer - Volume 55, Issues 15â16, July 2012, Pages 4043-4052
نویسندگان
Peng Yu,