کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
659835 1458117 2010 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A multi-layer porous wall model for coronary drug-eluting stents
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی جریان سیال و فرایندهای انتقال
پیش نمایش صفحه اول مقاله
A multi-layer porous wall model for coronary drug-eluting stents
چکیده انگلیسی

An analytical solution for solving the transient drug diffusion in adjoining porous wall layers faced with a drug-eluting stent is presented. The endothelium, intima, internal elastic lamina and media are all treated as homogeneous porous media and the drug transfer through them is modelled by a set of coupled partial differential equations. The classical separation of variables method for a multi-layer configuration is used. The model addresses the concept of penetration depth for multi-layer solids that is useful to treat the wall thickness by estimating a physical bound for mass diffusion. Drug concentration level and mass profiles in each layer at various times are given and discussed.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Heat and Mass Transfer - Volume 53, Issues 19–20, September 2010, Pages 3629–3637
نویسندگان
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