کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
660961 1458145 2008 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A dual reciprocity boundary element method for photothermal interactions in laser-induced thermotherapy
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی جریان سیال و فرایندهای انتقال
پیش نمایش صفحه اول مقاله
A dual reciprocity boundary element method for photothermal interactions in laser-induced thermotherapy
چکیده انگلیسی
Laser-induced thermotherapy (LITT) is a minimally invasive laser hyperthermia procedure for the treatment of localized tumors. Mathematical modeling of the photothermal processes in laser-irradiated tissues is essential for optimal treatment planning. In this study, A Monte Carlo method is introduced to simulate photon transport in the tumor tissues with complex geometries. The dual reciprocity boundary element method (DRBEM) is then formulated to solve the bioheat transfer equation in the tumors. The model is validated with the finite difference solutions. To illustrate the applications of the proposed DRBEM, several laser delivery schemes, including external laser irradiation, single or multiple laser fiber delivery applicators, are studied for tumors with regular or irregular geometric shapes. The temperature transients, laser energy distribution and coagulation patterns for different laser delivery modes are demonstrated. The unique advantages of the DRBEM, such as easy adaptability to complex tumor geometries and no need to discretize the inner domain, may make it well-suited and robust approach for predicting and controlling the temperature evolution in laser-induced thermotherapy procedure.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Heat and Mass Transfer - Volume 51, Issues 15–16, 15 July 2008, Pages 3869-3881
نویسندگان
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