Synthesis, catalytic oxidation and antimicrobial activity of copper(II) Schiff base complex

A new polymer supported Cu(II) Schiff base complex was synthesized. The solid complex was characterized by Fourier transform infrared spectroscopy (FT-IR), UV–vis diffuse reflectance spectroscopy (DRS), thermogravimetric analysis (TGA) and scanning electron microscope (SEM). Its homogeneous analogue was also prepared. The catalytic performances of the copper complex in oxidation reactions were evaluated for both homogeneous and heterogeneous systems. The copper(II) complex was found to be efficient catalyst for the oxidation of alkenes, alkanes and aromatic alcohols in the presence of hydrogen peroxide as oxidant at room temperature. The catalytic investigation revealed that the solid complex performs better than the homogeneous one as an oxidation catalyst. The solids containing the immobilized complex can be recovered from the reaction medium and reused almost five times, maintaining good catalytic activity. Furthermore, the in vitro toxicity of the ligand and complex was tested against the growth of bacterial species, viz., Staphylococcus aureus and Escherichia coli.

A polymer supported copper(II) Schiff base complex has been synthesized and characterized. The complex is tested as catalyst for the oxidation of various alkenes, alkanes and aromatic alcohols with 30% H2O2 in acetonitrile at room temperature. Moderate conversions and yield of products are obtained for the catalyst. Antibacterial activity was also studied with its homogeneous analogue.Figure optionsDownload high-quality image (81 K)Download as PowerPoint slideResearch highlights
► A new heterogeneous and homogeneous Cu(II) complex has been synthesized.
► Both Cu(II) complexes oxidized alkenes with 30% H2O2 in air at room temperature.
► Both Cu(II) complexes oxidized alkanes and aromatic alcohols under above conditions.
► Homogeneous Cu(II) complex shows antibacterial activity.
► Heterogeneous Cu(II) complex can be recycled up to five times.