Supercritical solvent selection (CO2versus ethane) and optimization of operating conditions of the extraction of lycopene from tomato residues: Innovative analysis of extraction curves by a response surface methodology and cost of manufacturing hybrid app

- Economic analysis and optimization of the SFE of lycopene from tomato residues.
- Hybrid RSM-COM approach for the analysis of any type of supercritical extraction curves.
- Costs of manufacturing (COM) in great agreement with lycopene solubility and extraction time.
- Comparative analysis of the SFE performance using supercritical CO2 or supercritical ethane.