Copper-free Sonogashira coupling reaction catalyzed by MCM-41-supported thioether palladium(0) complex in water under aerobic conditions

The MCM-41-supported thioether palladium(0) complex is a highly active catalyst for the copper-free Sonogashira coupling of aryl iodides with terminal alkynes in water at room temperature under aerobic conditions. This phosphine-free heterogeneous palladium catalyst can be easily recovered from the products and reused many times without loss of activity.

MCM-41-supported thioether palladium(0) complex is a highly active catalyst for the copper-free Sonogashira coupling of aryl iodides with terminal alkynes in water at room temperature under aerobic conditions. This phosphine-free heterogeneous palladium catalyst can be easily recovered from the products and reused many times without loss of activity. Figure optionsDownload as PowerPoint slide