Oxidative kinetic resolution of racemic secondary alcohols catalyzed by resin supported sulfonato-Mn(salen) complex in water

The oxidative kinetic resolution of racemic secondary alcohols catalyzed by resin supported sulfonato-Mn(salen) complex (R,R)-1 with good to excellent ee's in water in the presence of diacetoxyiodobenzene (PhI(OAc)2) is described. The resin supported (R,R)-1 was recovered quantitatively by simple filtration and reused for three times with consistent activity.

The oxidative kinetic resolution of racemic secondary alcohols catalyzed by resin supported sulfonato-Mn(salen) complex (R,R)-1 with good to excellent ee's in water in the presence of diacetoxyiodobenzene (PhI(OAc)2) is described. The resin supported (R,R)-1 was recovered quantitatively by simple filtration and reused for three times with consistent activity.Figure optionsDownload as PowerPoint slide