A modified and green Dakin–West reaction: An efficient and convenient method for a one-pot synthesis of β-acetamido carbonyl compounds

An efficient and improved procedure for the synthesis of β-acetamido carbonyl compounds is developed in the presence of trimethylsilyl chloride by a heteropolyacid catalyzed three-component coupling protocol.

An efficient and improved procedure for the synthesis of β-acetamido carbonyl compounds is developed in the presence of trimethylsilyl chloride by a heteropolyacid catalyzed three-component coupling protocol.Figure optionsDownload as PowerPoint slide