کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6814240 545617 2015 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Trajectories of premorbid childhood and adolescent functioning in schizophrenia-spectrum psychoses: A first-episode study
ترجمه فارسی عنوان
مسیرهای پیش از میلاد در دوران کودکی و نوجوانی در روان شناسی طیف اسکیزوفرنی: مطالعه ی اول
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی روانپزشکی بیولوژیکی
چکیده انگلیسی
Evidence of social and behavioral problems preceding the onset of schizophrenia-spectrum psychoses is consistent with a neurodevelopmental model of these disorders. Here we predict that individuals with a first episode of schizophrenia-spectrum psychoses will evidence one of three patterns of premorbid adjustment: an early deficit, a deteriorating pattern, or adequate or good social adjustment. Participants were 164 (38% female; 31% black) individuals ages 15-50 with a first episode of schizophrenia-spectrum psychoses. Premorbid adjustment was assessed using the Cannon-Spoor Premorbid Adjustment Scale. We compared the fit of a series of growth mixture models to examine premorbid adjustment trajectories, and found the following 3-class model provided the best fit with: a “stable-poor” adjustment class (54%), a “stable-good” adjustment class (39%), and a “deteriorating” adjustment class (7%). Relative to the “stable-good” class, the “stable-poor” class experienced worse negative symptoms at 1-year follow-up, particularly in the social amotivation domain. This represents the first known growth mixture modeling study to examine premorbid functioning patterns in first-episode schizophrenia-spectrum psychoses. Given that the stable-poor adjustment pattern was most prevalent, detection of social and academic maladjustment as early as childhood may help identify people at increased risk for schizophrenia-spectrum psychoses, potentially increasing feasibility of early interventions.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Psychiatry Research - Volume 227, Issues 2–3, 30 June 2015, Pages 339-346
نویسندگان
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