کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6815412 | 545708 | 2013 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Neuropsychological correlates of symptom dimensions in inpatients with major depressive disorder
ترجمه فارسی عنوان
ارتباطات عصب روان شناختی ابعاد علامت در بیماران بستری با اختلال افسردگی عمده
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کلمات کلیدی
افسردگی، ابعاد نشانه، اختلال عصب روانشناختی،
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
روانپزشکی بیولوژیکی
چکیده انگلیسی
Symptoms of major depressive disorder (MDD) manifest variably across individuals. Accordingly, recent models of the disorder imply that MDD may be characterized according to independent symptom dimensions. In particular, several studies reveal that depression may be characterized along dimensions of negative affect, agitation and hostility, and lassitude and malaise. No research has examined the relationship between these dimensions and neuropsychological function. Towards this end, 133 in patients with unipolar MDD and 17 people without psychiatric illness were administered a brief battery of neuropsychological tests and the MMPI-2. Paralleling earlier research, principal component analysis of the MMPI-2 revealed symptom dimensions of negative affect, agitation, and lassitude and malaise. Multiple regression analyses showed that the negative affect and agitation dimensions accounted for significant variance on measures of executive function, speed of information processing, new learning, dexterity, and overall impairment. Lassitude and malaise failed to correspond with neuropsychological performance. Implications of these data for clinical practice and neural models of MDD are discussed.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Psychiatry Research - Volume 207, Issues 1â2, 15 May 2013, Pages 61-67
Journal: Psychiatry Research - Volume 207, Issues 1â2, 15 May 2013, Pages 61-67
نویسندگان
Michael Basso, Dennis Combs, Rod Purdie, Phillip Candilis, Robert Bornstein,