کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
684734 889026 2007 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The production of polyhydroxyalkanoates in recombinant Escherichia coli
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی تکنولوژی و شیمی فرآیندی
پیش نمایش صفحه اول مقاله
The production of polyhydroxyalkanoates in recombinant Escherichia coli
چکیده انگلیسی

Polyhydroxyalkanoates, the natural polyester that many microorganisms accumulate to store carbon and reducing equivalents, have been considered as a future alternative of traditional plastic due to their special properties. In Escherichia coli, a previous non-polyhydroxyalkanoates producer, pathway engineering has been developed as a very powerful approach to set up microbial production process through the introduction of direct genetic changes by recombinant DNA technology. Various metabolic pathways leading to the polyhydroxyalkanoates accumulation with desirable properties at low-cost and high-productivity have been developed. At the same time, high density fermentation technology of E. coli provides an efficient polyhydroxyalkanoates production strategy. This review focused on metabolic engineering, fermentation and downstream process aiming to polyhydroxyalkanoates production in E. coli.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioresource Technology - Volume 98, Issue 12, September 2007, Pages 2313–2320
نویسندگان
, , ,