کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6892353 | 1445355 | 2017 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Transdermal iontophoresis-A quantitative and qualitative study
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی کامپیوتر
علوم کامپیوتر (عمومی)
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چکیده انگلیسی
The use of enhancers to increase the drug molecules penetration into target tissues is a usual technique in drug delivery. In transdermal drug delivery, electric fields are often used to increase the drug transport through the skin. In this paper we study a drug delivery mechanism from a reservoir which is in contact with the skin. We assume that the drug transport in the coupled system is enhanced by a small electric field that induces a convective field. We establish energy estimates for the coupled system and we propose a semi-analytical discrete coupled model that mimics the continuous model. The qualitative behaviour of the system is illustrated.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Computers & Mathematics with Applications - Volume 74, Issue 10, 15 November 2017, Pages 2231-2242
Journal: Computers & Mathematics with Applications - Volume 74, Issue 10, 15 November 2017, Pages 2231-2242
نویسندگان
J.A. Ferreira, P. de Oliveira, G. Pena,