Sulfonic acid functionalized silica: A remarkably efficient heterogeneous reusable catalyst for α-monobromination of carbonyl compounds using N-bromosuccinimide

Sulfonic acid functionalized silica has been found to be a highly efficient and versatile catalyst for α-monobromination of carbonyl compounds (cyclic and acyclic ketones, 1,3-diketones, β-ketoesters, lactones, coumaranones and lactams) using N-bromosuccinimide under mild reaction conditions. The α-monobrominated products were obtained in very high yields and in short reaction times. The catalyst works under heterogeneous conditions and can be recyclable.

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