Ion exchange resins as recyclable and heterogeneous solid acid catalysts for the Biginelli condensation: An improved protocol for the synthesis of 3,4-dihydropyrimidin-2-ones

A simple and efficient protocol has been developed for the synthesis of 3,4-dihydropyrimidin-2-ones using ion exchange resins as recyclable, heterogeneous, environmentally benign catalysts under mild reaction conditions. Among the various solid acid catalysts Nafion NR-50 was found to be most efficient catalyst.

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