A poly(glycerol sebacate)-coated mesoporous bioactive glass scaffold with adjustable mechanical strength, degradation rate, controlled-release and cell behavior for bone tissue engineering

- A PGS-coated MBG hierarchical scaffold for bone repair was designed and prepared.
- The physicochemical properties of the PGS/MBG scaffold can be modulated.
- Uncrosslinked PGS enhances the compressive strength and toughness of MBG scaffold.
- This scaffold combines MBG's osteoinductivity and PGS's proliferation promotion.
- Uncrosslinked PGS-induced scaffold comprehensive improvement is first investigated.