Sorption and release of drugs in/from cross-linked poly(ethyleneimine) multilayer films deposited onto silica microparticles

- Build up and cross-linking of single PEI multilayers by pyromellitic dianhydride.
- Lower concentration of cross-linker higher sorption of sodium diclofenac and indomethacin.
- Langmuir and Sips isotherms fitted well the sorption of indomethacin.
- Percentage of drug release depended on drug structure and cross-linker content.