Enhanced specific absorption rate in silanol functionalized Fe3O4 core-shell nanoparticles: Study of Fe leaching in Fe3O4 and hyperthermia in L929 and HeLa cells

- Water dispersible Fe3O4-SiO2 shows high SAR value in AC magnetic field and less leaching of Fe in pH = 2-7.
- Effect of surface coating on specific absorption rate (SAR) under alternating magnetic field (AMF) is investigated.
- Cells treated with MNPs along with induction heating show decrease in viability as compared to that without induction heating.
- Further, cell death is found to be ∼55% more in cells treated with silica coated MNPs under induction heating as compared to untreated control.