The role of 2-methyl-2, 4-pentanediol in sodium dodecyl sulfate micelle dissociation unveiled by dynamic light scattering and molecular dynamics simulations

- SDS micelle dissociation was observed in presence of molar concentrations of MPD.
- Combination of experimental and theoretical methods allows reaching the mechanism.
- MPD screens the negative charge on the SDS headgroups leading to micelle deformation.
- Then, MPD interacts with the hydrophobic tails allowing the micelle dissociation.