Potentiation of 5-fluorouracil encapsulated in zeolites as drug delivery systems for in vitro models of colorectal carcinoma

- Potentiation of 5-FU was carried out with Y and LTL zeolites.
- 5-FU release from the zeolites was explained by the Weibull model.
- DDS efficacy was evaluated in vitro models of colorectal carcinoma.
- Significant potentiation of the 5-FU effect on the cell viability by the DDS.
- Immunofluorescence studies provided evidence for zeolite-cell internalization.