Drug resistance reversal activity of anticancer drug loaded solid lipid nanoparticles in multi-drug resistant cancer cells

- SLN can increase the transport anticancer drugs (PTX or DOX) into cancer cells.
- SLN enhance cytotoxicity against drug sensitive cells and multi-drug resistant cells.
- SLN protect drug into cells from P-gp's efflux to overcome multi-drug resistance.
- SLN is a promising effective system for reversal in drug resistant cancer cells.