A multifunctional mesoporous silica nanocomposite for targeted delivery, controlled release of doxorubicin and bioimaging

- Multifunctionalized MSN was synthesized for drug delivery and bioimaging.
- Carboxyl functionalization made the drug delivery system pH-dependent.
- Folate modification significantly enhanced the cellular uptake.
- The introduction of PEG increased the water dispersibility.
- The conjunction of biolabel Cy5 made the system effective for bioimaging.