Process optimization of a multi-product biorefinery: The effect of biomass seasonality

- A process optimization method is proposed for problems with seasonal feedstock.
- A multiproduct biorefinery with multiple seasonal biomass feedstock was optimized.
- Biomass composition has a significant effect on the optimal biorefinery flowsheet.
- Levulinic acid production is convenient for high cellulose/hemicellulose ratio.
- Product yield distribution is affected by biomass seasonality.