Temperature regulates fatty acid desaturases at a transcriptional level and modulates the fatty acid profile in the Antarctic microalga Chlamydomonas sp. ICE-L

► Potential FA desaturation metabolic pathway of the microalga was displayed. ► For the first time the five FADs have been analyzed together. ► ω3CiFADs are of vital consequence to acclimation low temperatures. ► PUFAs were significantly increased at 0 and 5 °C, while decreased at 15 °C.