Microtiter plates versus stirred mini-bioreactors in biocatalysis: A scalable approach

► A scaled down approach to identify and optimize operational conditions was developed. ► A set of parallel bioreactors system was designed, developed and operated. ► The influence of geometric and dynamic parameters on bioconversion rate was established. ► Development of a scalable, fully controlled and monitored biocatalysis process. ► Optimized naringin hydrolysis by naringinase encapsulated in PVA-lens.