Experimental mixture design as a tool to enhance glycosyl hydrolases production by a new Trichoderma harzianum P49P11 strain cultivated under controlled bioreactor submerged fermentation

► Glycosyl hydrolases (GH) play a vital role in the conversion of biomass into biofuels. ► Experimental mixture design is a powerful tool in bioprocess development. ► Growth conditions can significantly influence GH biosynthesis. ► The Amazon rainforest T. harzianum strain is a useful candidate for GH production.