Antibiotic Fermentation Broth Treatment by a pilot upflow anaerobic sludge bed reactor and kinetic modeling

► Anaerobic fermentation broth could be efficiently treated by upflow anaerobic sludge blanket (UASB) reactor. ► The highest chemical oxygen demand (COD) removal efficiency was obtained as 95.7%. ► The highest methane production rate was 0.30LmethanegCODremoved-1. ► The results of the study were interpreted using the various kinetic models. ► The results showed a close relationship with all kinetic models used.