Overexpression and characterization of a novel (S)-specific extended short-chain dehydrogenase/reductase from Candida parapsilosis

► The optical purity of the chiral product (S)-CHBE was over 99% enantiomeric excess. ► The molar conversion yield of CHBE was 91.1%. ► The apparent km value for COBE is an order of magnitude lower than that of other enzymes.