The effect of different trophic modes on lipid accumulation of Scenedesmus quadricauda

► The effect of different trophic modes on lipid production of Scenedesmus quadricauda was studied. ► S. quadricauda could grow on photoautotrophic, heterotrophic and mixotrophic modes. ► Different CO2 and glucose concentrations affected cell and lipid yield significantly. ► Maximum lipid content was obtained in mixotrophic culture. ► It is feasible to culture microalgae for lipid production in wastewater.