کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
710339 892109 2016 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Multi-Objective Optimal Control Study of Fed-Batch Bio-Reactor*
ترجمه فارسی عنوان
کنترل چندمرحله ای بهینه کنترل زیستی راکتور فدرال بچ
کلمات کلیدی
منطقه قابل دسترس بهینه سازی چند هدفه، مرتب سازی مش، راکتور فید بچ کنترل بهینه
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مکانیک محاسباتی
چکیده انگلیسی

Evolutionary Algorithms have been successfully applied for offline optimal control problems of fed-batch bio-reactors. In such problems, productivity-yield maximization is carried out by optimizing the transient feed recipe. However, this is usually done for a fixed fed-batch time. The optimum batch time can be computed by solving single objective optimal control problems multiple times with different fed-batch times. Since this approach is quite computationally expensive, we in this work formulate a multi-objective optimization (MOO) problem to find the minimum fed-batch time along with maximizing productivity-yield. Such an MOO approach will result in saving significant computational effort. A single parameter based fast mesh sorting with multi objective differential evolution is used in this work for solving MOO problems. We have considered a case study of optimal control of fed-batch reactor for secreted protein production with volume constraint in this work.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: IFAC-PapersOnLine - Volume 49, Issue 7, 2016, Pages 97–102
نویسندگان
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