کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7229153 | 1470917 | 2018 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Direct electrochemical reduction of hematite decorated graphene oxide (α-Fe2O3@erGO) nanocomposite for selective detection of Parkinson's disease biomarker
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
An unusual approach is reported herein to fabricate magnetic hematite (α-Fe2O3) decorated electrochemically reduced graphene oxide (α-Fe2O3@erGO) nanocomposite. The method utilizes direct electrochemical reduction of self-assembled, ex-situ synthesized α-Fe2O3 anchored GO to erGO (α-Fe2O3@erGO) on glassy carbon electrode (GCE) for selective detection of dopamine (DA), an important biomarker of Parkinson's disease. The formation of α-Fe2O3@erGO/GCE has been confirmed by XPS and Raman spectroscopy. α-Fe2O3@erGO modified GCE exhibits synergistic catalytic activity nearly 2.2 and 5 fold higher than α-Fe2O3@GO and other modified electrodes, respectively towards oxidation of DA. The fabricated sensor exhibited linear dynamic ranges over 0.25â¯ââ¯100â¯ÂµM in response to DA with a LOD of 0.024â¯ÂµM (S/Nâ¯=â¯3), LOQ of 0.08â¯ÂµM (S/Nâ¯=â¯10), and a sensitivity of 12.56â¯ÂµAâ¯ÂµM-1 cm-2. Finally, the practical analytical application of the proposed α-Fe2O3@erGO/GCE was investigated for the determination of DA in commercially available pharmaceutical formulation and human serum samples, and showed satisfactory recovery results towards DA.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biosensors and Bioelectronics - Volume 115, 15 September 2018, Pages 53-60
Journal: Biosensors and Bioelectronics - Volume 115, 15 September 2018, Pages 53-60
نویسندگان
Georgeena Mathew, Parama Dey, Rituparna Das, Sreemayee Dutta Chowdhury, Merina Paul Das, Pandiyarasan Veluswamy, Bernaurdshaw Neppolian, Jayabrata Das,