کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7231293 1470956 2016 49 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Membrane-based lateral flow immunochromatographic strip with nanoparticles as reporters for detection: A review
ترجمه فارسی عنوان
نوار ایمنی کروماتوگرافی جریان جانبی غشایی با نانوذرات به عنوان خبرنگار برای تشخیص: یک بررسی
کلمات کلیدی
نوار جریان ایمونوکروماتوگرافی جانبی، نانوذرات رنگی، نانوذرات لومینسانس، نانوذرات مغناطیسی، تشخیص
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی
Membrane-based lateral flow immunochromatographic strip (LFICS) is widely used in various fields because of its simplicity, rapidity (detection within 10 min), and low cost. However, early designs of membrane-based LFICS for preliminary screening only provide qualitative (“yes/no” signal) or semi-quantitative results without quantitative information. These designs often suffer from low-signal intensity and poor sensitivity and are only capable of single analyte detection, not simultaneous multiple detections. The performance of existing techniques used for detection using LFICS has been considerably improved by incorporating different kinds of nanoparticles (NPs) as reporters. NPs can serve as alternative labels and improve analytical sensitivity or limit of detection of LFICS because of their unique properties, such as optical absorption, fluorescence spectra, and magnetic properties. The controlled manipulation of NPs allows simultaneous or multiple detections by using membrane-based LFICS. In this review, we discuss how colored (e.g., colloidal gold, carbon, and colloidal selenium NPs), luminescent (e.g., quantum dots, up-converting phosphor NPs, and dye-doped NPs), and magnetic NPs are integrated into membrane-based LFICS for the detection of target analytes. Gold NPs are also featured because of their wide applications. Different types and unique properties of NPs are briefly explained. This review focuses on examples of NP-based LFICS to illustrate novel concepts in various devices with potential applications as screening tools. This review also highlights the superiority of NP-based approaches over existing conventional strategies for clinical analysis, food safety, and environmental monitoring. This paper is concluded by a short section on future research trends regarding NP-based LFICS.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biosensors and Bioelectronics - Volume 75, 15 January 2016, Pages 166-180
نویسندگان
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