کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7231650 1470958 2015 26 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Reduced graphene oxide modified smart conducting paper for cancer biosensor
ترجمه فارسی عنوان
مقاله هوشمند هدایت کاغذ اصلاح شده برای اکسید گرافین برای بیوسنسور سرطانی کاهش یافته است
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی
We report results of the studies relating to the fabrication of a paper based sensor comprising of poly (3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) and reduced graphene oxide (RGO) composite. The effect of various solvents like methanol, ethylene glycol and H2SO4 on the electrical conductivity of PEDOT:PSS coated Whatman paper has been investigated. The conductivity of this solution processed conducting paper significantly increases from ~1.16×10−4 S cm−1 up to ~3.57×10−2 S cm−1 (~300 times) on treatment with ethylene glycol. The observed significant increase in electrical conductivity is due to conformational rearrangement in the polymer and is due to strong non-covalent cooperative interaction between PEDOT and the cellulose molecules. Further, incorporation of RGO into the conducting paper results in improved electrochemical performance and signal stability. This paper electrode is a promising alternative over the expensive conventional electrodes (ITO, gold and glassy carbon), that are known to have limited application in smart point-of-care (POC) devices. This low cost, flexible and environment friendly conducting paper based biosensor utilized for cancer biomarker (carcinoembryonic antigen, CEA) detection reveals high sensitivity of 25.8 µA ng−1 mL cm−2 in the physiological range, 1-10 ng mL−1.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biosensors and Bioelectronics - Volume 73, 15 November 2015, Pages 114-122
نویسندگان
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