کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7232976 | 1470970 | 2014 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Hand-drawn&written pen-on-paper electrochemiluminescence immunodevice powered by rechargeable battery for low-cost point-of-care testing
ترجمه فارسی عنوان
سیستم ایمنی بدن الکتروشیمیومینسانس دست نوشته شده و نوشته شده بر روی کاغذ باتری قابل شارژ برای آزمایش هزینه کم هزینه
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کلمات کلیدی
قلم روی کاغذ، دست کشیده، دست نویس، الکتروشیمیومومسانس ایمونوسنسور، تست نقطه مراقبت،
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی
In this paper, a pen-on-paper electrochemiluminescence (PoP-ECL) device was entirely hand drawn and written in commercially available crayon and pencil in turn for the first time, and a constant potential-triggered sandwich-type immunosensor was introduced into the PoP-ECL device to form a low-cost ECL immunodevice proof. Each PoP-ECL device contained a hydrophilic paper channel and two PoP electrodes, and the PoP-ECL device was produced as follows: crayon was firstly used to draw hydrophobic regions on pure cellulose paper to create the hydrophilic paper channels followed with a baking treatment, and then a 6B-type black pencil with low resistivity was applied for precision writing, as the PoP electrodes, across the hydrophilic paper channel. For further point-of-care testing, a portable, low-cost rechargeable battery was employed as the power source to provide constant potential to the PoP electrodes to trigger the ECL. Using Carbohydrate antigen 199 as model analyte, this PoP-ECL immunodevice showed a good linear response range from 0.01-200Â UÂ mLâ1 with a detection limit of 0.0055Â UÂ mLâ1, a high sensitivity and stability. The proposed PoP-ECL immunodevice could be used in point-of-care testing of other tumor markers for remote regions and developing countries.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biosensors and Bioelectronics - Volume 61, 15 November 2014, Pages 21-27
Journal: Biosensors and Bioelectronics - Volume 61, 15 November 2014, Pages 21-27
نویسندگان
Hongmei Yang, Qingkun Kong, Shaowei Wang, Jinmeng Xu, Zhaoquan Bian, Xiaoxiao Zheng, Chao Ma, Shenguang Ge, Jinghua Yu,