Electrochemical sensor based on magnetic molecularly imprinted nanoparticles at surfactant modified magnetic electrode for determination of bisphenol A

A selective electrochemical sensor based on magnetic molecularly imprinted nanoparticles was developed for determination of bisphenol A (BPA). The particles with regular morphology, high saturation magnetization and good monodispersion were prepared. The hydrophilicity, sensitivity and anti-fouling of the sensor were enhanced by modifying carbon paste electrode with surfactant CTAB in advanced. The results demonstrated that the response of BPA on imprinted electrode was 2.6 times as much as that on non-imprinted sensor. Moreover, the separation factors of BPA to β-estradiol, estriol and diethylstilbestrol were 16.5, 17.3 and 6.6, respectively. Under optimized conditions, the currents were found to be proportional to the BPA concentrations in the range of 6.0×10−7-1.0×10−4 mol/L with a detection limit of 1.0×10−7 mol/L (S/N=3). A rapid response of the imprinted sensor was obtained within 3 min. The developed sensor was successfully used for determination of BPA in actual samples such as drink bottles and lake water.