Multifunctional core-shell nanoplatforms (gold@graphene oxide) with mediated NIR thermal therapy to promote miRNA delivery

Here, introduces smart gene delivery systems base core-shell nanoplatforms (Au@GO) with different shapes that the outer shell of them are functionalized by PEG as well as poly-L-arginine with various length. Presented nanoplatforms would remarkably target cancer cells, internalize and release their payload. Thermal therapy also applied and represented synergic with gene to perform noticeable result in activate apoptotic pathways and suppress breast cancer cells.174