کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7267150 | 1473038 | 2016 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Elevated cortisol in healthy female adolescent offspring of mothers with posttraumatic stress disorder
ترجمه فارسی عنوان
افزایش کورتیزول در تولد نوزادان سالم مادران مبتلا به اختلال استرس پس از سانحه
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
روانپزشکی و بهداشت روانی
چکیده انگلیسی
Offspring with maternal PTSD are at increased risk of developing PTSD themselves. Alterations in the hypothalamic-pituitary-adrenal (HPA) axis may play a role and have been noted in offspring, although evidence is mostly from adult offspring with PTSD symptoms themselves. The present study of adolescent girls (N = 472) and their mothers (n = 18 with lifetime PTSD versus n = 454 with no PTSD) sought to determine whether healthy, non-affected offspring of mothers with PTSD would exhibit altered HPA axis function. Saliva samples were collected from the adolescent girls at waking, 30 min after waking, and 8 pm on 3 consecutive days. Offspring whose mothers were diagnosed with PTSD demonstrated higher cortisol awakening response (CAR; Cohen's d = 0.58) and greater total cortisol output (Cohen's d = 0.62). In this preliminary study, higher cortisol levels during adolescence among offspring of mothers with PTSD may index a vulnerability in these at-risk youth.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Anxiety Disorders - Volume 40, May 2016, Pages 37-43
Journal: Journal of Anxiety Disorders - Volume 40, May 2016, Pages 37-43
نویسندگان
Keke Liu, Camilo J. Ruggero, Brandon Goldstein, Daniel N. Klein, Greg Perlman, Joan Broderick, Roman Kotov,