کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7284300 | 1474037 | 2015 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Reversing Ribot: Does regression hold in language of prodromal Alzheimer's disease?
ترجمه فارسی عنوان
معکوس کردن ریبوت: آیا رگرسیون در زبان بیماری آلزایمر پیشگیری می کند؟
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کلمات کلیدی
زبان، اختلال شناختی خفیف، سالخورده، ریبوت، فرضیه رگرسیون، رشد کودک،
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
روانپزشکی بیولوژیکی
چکیده انگلیسی
We consider the regression or retrogenesis hypothesis, which argues that order of acquisition in development is reversed in neurodegeneration or pathology. Originally proposed as a regression hypothesis for the study of memory disorders, specifically retrograde amnesia, by Ribot (1881), it has been extended to the study of brain aging and pathology and to language. We investigate this hypothesis in a new study of language development, aging, and pathology. Through interuniversity collaboration using a matched experimental design and task, we compare production of complex sentences containing relative clauses by normal monolingual children during normal development, healthy young adults, healthy aging adults, and aging adults diagnosed with mild cognitive impairment, a recognized potential harbinger of Alzheimer's disease. Our results refute the regression hypothesis in this area and lead to potential syntactic markers for prodromal Alzheimer's disease and predictions for future brain imaging analyses.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brain and Language - Volume 143, April 2015, Pages 1-10
Journal: Brain and Language - Volume 143, April 2015, Pages 1-10
نویسندگان
Barbara Lust, Suzanne Flynn, Janet Cohen Sherman, James Gair, Charles R. Jr., Claire Cordella, Jordan Whitlock, Sarah Mancuso, Zhong Chen, Aileen Costigan, Alex Immerman,