The other side of the coin: Blunted cardiovascular and cortisol reactivity are associated with negative health outcomes

► Blunted reactions to acute laboratory stress relate to poor health outcomes. ► Blunting may reflect reduced effort, stress perceptions, or physiological capacity. ► Blunted responses may be a marker of central motivational dysregulation. ► Blunted reactivity is neurally based and independent of stress task effort.