کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7296592 | 1474476 | 2009 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Excessive compensatory recruitment as a compulsory neurophysiological mechanism in Very Early Alzheimer's Disease as compared to Mild Vascular Dementia and to age-matched normal controls
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موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب رفتاری
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چکیده انگلیسی
These findings suggest that the delayed P450 latencies found over pre-frontal and frontal regions in both patient populations, reflect the partial disconnection of their neuronal pathways from limbic structures. Specifically, in VEAD patients, this aspect, along with the abnormally high amplitudes found over parietal and occipital regions, support the conclusion that VEAD patients allocate much more cerebral physiological resources and effort to accomplish the memory workload tasks as opposed to age-matched normal controls and to MVD patients. As such, in VEAD, the excessive recruitment of compensatory neuronal pools becomes a compulsory neurophysiological mechanism to meet the demanding tasks of our Memory Workload Paradigm.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Psychophysiology - Volume 73, Issue 2, August 2009, Pages 164-169
Journal: International Journal of Psychophysiology - Volume 73, Issue 2, August 2009, Pages 164-169
نویسندگان
Helen Beuzeron-Mangina, Constantine A. Mangina,