Dissociable roles of the dorsal striatum and dorsal hippocampus in conditional discrimination and spatial alternation T-maze tasks

► Dorsal striatum inactivation disrupts conditional discrimination (CD) performance. ► Dorsal hippocampal inactivation disrupts spatial alternation performance. ► Rats exhibit response behavior after inactivation of both brain regions. ► Comparison between the two tasks allows for the control of confounding variables. ► Results characterize the contributions of these two brain areas to CD performance.