Post-training disruption of Arc protein expression in the anterior cingulate cortex impairs long-term memory for inhibitory avoidance training

► Arc protein is elevated in the ACC after inhibitory avoidance (IA) training. ► Post-training intra-ACC oligodeoxynucleotide infusions impair long-term memory for IA. ► Like in the hippocampus Arc protein is elevated in the ACC 8 h after training. ► Disruption of Arc protein expression 6 h after training impairs long-term memory.