کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7319402 1475573 2016 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Distinguishing between impairments of working memory and inhibitory control in cases of early dementia
ترجمه فارسی عنوان
تشخیص بین اختلالات حافظه کاری و کنترل مهاری در موارد زودرس
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
چکیده انگلیسی
Dementia (most notably, Alzheimer's Disease) is often associated with impairments of both working memory and inhibitory control. However, it is unclear whether these are functionally distinct impairments. We addressed the issue of whether working memory and inhibitory control can be dissociated, using data from a sample of patients who were recruited in a longitudinal study (Crawford et al., 2013, Crawford et al., 2015). The first case revealed a preserved working memory capacity together with poor inhibitory control in the anti-saccade task. A longitudinal follow-up revealed that the defective inhibitory control emerged 12-months before the dementia was evident on the mini-mental state examination assessment. A second case revealed a poor working memory together with a well-preserved level of inhibitory control. The dissociation of working memory and inhibitory control was confirmed statistically in 7 additional cases. These findings yield converging evidence that working memory and inhibitory control are distinct cognitive operations and challenges the Kimberg and Farah (2000) cognitive model of working memory.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuropsychologia - Volume 81, 29 January 2016, Pages 61-67
نویسندگان
, ,