کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7584418 | 1492026 | 2018 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Simultaneous determination of aminoglycosides and colistins in food
ترجمه فارسی عنوان
تعیین همزمان آمینوگلیکوزید ها و کلستین ها در مواد غذایی
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کلمات کلیدی
آمینوگلیکوزید، کالیستین ها، عضله، شیر، کروماتوگرافی مایع با طیف سنجی توده ای با وضوح بالا، اعتبار سنجی روش،
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی
A novel method for the simultaneous identification and quantification of twelve aminoglycosides (AGs) and two colistins in meat and bovine milk has been developed. The analysis was carried out using liquid chromatography coupled to quadrupole-Orbitrap mass spectrometry (LC-Q-Orbitrap). Among the HILIC (Hydrophilic Interaction Liquid Chromatography) stationary phases tested, the bare silica Poroshell 120 provided the best results. The samples were extracted with an aqueous solution followed by an SPE clean up based on the weak cation exchange mechanism. The validation study was performed carrying out 72 experiments per matrix at six different concentrations in a range encompassing the Maximum Residue Limits. The recoveries were from 72 to 87% in meat (except colistins) and from 82 to 96% in milk. Repeatabilities and intra-lab reproducibilities were lower than 10 and 15%, respectively. Limits of detection were lower than or equal to 33â¯Âµgâ¯kgâ1. Finally, test materials containing AGs prepared for interlaboratory studies were successfully analysed.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Chemistry - Volume 266, 15 November 2018, Pages 9-16
Journal: Food Chemistry - Volume 266, 15 November 2018, Pages 9-16
نویسندگان
G. Saluti, I. Diamanti, D. Giusepponi, L. Pucciarini, R. Rossi, S. Moretti, R. Sardella, R. Galarini,